Dziko lapansi ndi chilengedwe chovuta, ndipo malo athu momwemo amadalira zinthu zambiri.Kuchokera ku thanzi la dothi kupita ku khalidwe la mpweya kupita ku khalidwe la zomera ndi tizilombo tating'onoting'ono, kumvetsetsa chilengedwe chathu ndi anthu ena okhalamo n'kofunika kwambiri kuti tikhale ndi moyo.Pamene nyengo ikupitirizabe kusintha, kuphunzira chilengedwe ndi mitundu yake yosiyanasiyana ya moyo kudzakhala kofunika kwambiri.
Mu Okutobala 2023, Advanced Photon Source (APS), malo ogwiritsa ntchito mkati mwa Ofesi ya Sayansi ku US Department of Energy's (DOE) Argonne National Laboratory, idzakhazikitsa mwalamulo pulogalamu yatsopano yokulitsa luso lofufuza ndi kusanthula zachilengedwe ndi chilengedwe ma laboratories otsogola padziko lonse lapansi.X-ray munda.Kampani yotchedwa eBERlight posachedwapa idalandira chilolezo kuchokera ku US Department of Energy's Biological and Environmental Research (BER) pulogalamu.Cholinga chake ndikulumikiza ofufuza omwe akuchita zoyeserera pa ntchito ya BER ndi zida zasayansi za X-ray zotsogola padziko lonse za APS.Pokulitsa mwayi wofikira ku kuthekera kosiyanasiyana kwa APS, oganiza bwino a eBERlight akuyembekeza kupeza njira zatsopano zasayansi ndikukopa magulu atsopano a ofufuza kuti afufuze malingaliro atsopano pa dziko lomwe tikukhalamo.
"Uwu ndi mwayi wopanga china chatsopano chomwe sichinakhalepo mu APS m'mbuyomu," adatero Argonne National Laboratory protein crystalologist Caroline Michalska, yemwe akutsogolera ntchito pa eBERlight. â�<“我們正在扩大准入范围，以适应更多的生物和环境研穿，并且由于该用范划是如武比新，因家正在帮助我們开发它。” â�<“我們正在扩大准入范围，以适应更多的生物和环境研究，并且由于该该划是如此新，因"Tikukulitsa mwayi woti tithandizire kafukufuku wambiri wazachilengedwe komanso zachilengedwe, ndipo chifukwa pulogalamuyi ndi yatsopano, asayansi omwe adzagwiritse ntchito malowa akutithandiza kuikulitsa."
Kuyambira kukhazikitsidwa kwake mu 1990s, APS yakhala mtsogoleri pazambiri za "macromolecular crystallography" pakufufuza kwachilengedwe.Asayansi akugwiritsa ntchito ukadaulo uwu kuphunzira zambiri za matenda opatsirana ndi ma virus kuti akhazikitse maziko a katemera ndi chithandizo.APS tsopano ikufuna kupititsa patsogolo kupambana kwake kumadera ena a moyo ndi sayansi ya chilengedwe.
Vuto limodzi pakukula kumeneku ndilakuti asayansi ambiri azachilengedwe komanso zachilengedwe sadziwa za kuthekera kwa APS kuwathandiza kupititsa patsogolo kafukufuku wawo ndipo sadziwa njira yopangira ma X-ray owala a chinthu.Momwemonso, asayansi ambiri sadziwa kuti ndi malo ati oyesera a APS ambiri, otchedwa beamlines, omwe ali abwino kwambiri pazoyeserera zawo, popeza siteshoni iliyonse imakongoletsedwa ndi sayansi ndiukadaulo.
Michalska adati apa ndipamene eBERlight imayamba kusewera.Adafotokozanso kuti ndi chilengedwe chopangidwa kuti chilumikizane ndi asayansi ndi matekinoloje oyenera panjira yoyenera ya APS.Ofufuza apereka malingaliro kwa ogwira ntchito ku eBERlight omwe athandizire kugwirizanitsa mapangidwe oyesera ndi njira yoyenera yochitira kafukufukuyu.Anati kusiyanasiyana kwa kuthekera kwa APS kumatanthauza kuti eBERlight ikhoza kukhudza mbali zingapo za biology ndi sayansi ya chilengedwe.
"Tikuyang'ana zomwe ofufuza a BER akuphunzira komanso momwe tingathandizire kafukufukuyu," adatero. â�<“其中一些研究人员从未使用过APS 等同步加速器. â�<“其中一些研究人员从未使用过APS 等同步加速器."Ena mwa ofufuzawa sanagwiritsepo ntchito synchrotron ngati APS.Amaphunzira zida zomwe zilipo komanso mafunso asayansi omwe angayankhidwe ku APS zomwe sizingachitike kwina.”
"Uwu ndi mwayi wopanga china chatsopano chomwe sichinakhalepo mu APS m'mbuyomu.Tikukulitsa kuchuluka kwa kafukufuku wa zamoyo ndi zachilengedwe, ndipo chifukwa uwu ndi kafukufuku watsopano, asayansi omwe adzagwiritse ntchito malowa akutithandiza kupanga polojekitiyi.- Caroline Michalska, Argonne National Laboratory
Ponena za sayansi yeniyeni yomwe eBERlight idzalimbikitsa, Michalska adanena kuti idzaphatikizapo chirichonse kuchokera kufukufuku wa nthaka kupita ku zomera zomwe zikukula, kupanga mitambo ndi biofuels.Stefan Vogt, wachiwiri kwa director of the APS X-ray Science Division, adawonjezera kayendedwe kamadzi pamndandandawo, ponena kuti chidziwitsochi ndi chofunikira kuti timvetsetse bwino kusintha kwanyengo.
"Tikuphunzira mafunso okhudzana ndi sayansi ya nyengo, ndipo tiyenera kupitiriza kuwaphunzira," adatero Vogt. â�<“我們需要了解如何应对气候变化对环境的深远影响。” â�<“我們需要了解如何应对气候变化对环境的深远影响。”"Tiyenera kumvetsetsa momwe tingathanirane ndi zotsatira zakusintha kwanyengo."
Pomwe eBERlight idakhazikitsidwa mwalamulo mu Okutobala, APS ikhalabe pakanthawi kwa chaka ngati gawo lokonzanso malo.Panthawiyi, gululi lidzagwira ntchito yofufuza ndi kupanga njira zowonetsera zachilengedwe ndi zachilengedwe, kupanga nkhokwe, ndi kuyendetsa pulogalamuyo.
APS ikabweranso pa intaneti mu 2024, kuthekera kwake kudzakulitsidwa kwambiri.Gulu la eBERlight lidzalowa m'mapangano a nthawi yayitali ndi mayendedwe a 13 APS omwe akuyimira umisiri wosiyanasiyana.Asayansi omwe akugwira ntchito kudzera pa eBERlight adzakhalanso ndi mwayi wopeza zida za Argonne, monga Argonne Computing Facility, komwe kuli maofesi apamwamba a DOE Office of Science Office of Science ndi ma laboratory supercomputers, ndi Center for Advanced Protein Characterization, komwe mapuloteni amawunikiridwa ndikukonzekera kusanthula.
Pamene pulogalamuyo ikupita, idzakulitsa kulumikizana ndi malo ena ogwiritsa ntchito a DOE Office of Science, monga Pacific Northwest National Laboratory's Environmental Molecular Sciences Laboratory ndi Joint Genome Institute ku Lawrence Berkeley National Laboratory.
"Pamafunika mudzi kuti ulere mwana, koma pamafunika mudzi waukulu kwambiri kuti uthetse vuto la sayansi," anatero katswiri wa sayansi ya sayansi ya Argonne Zou Finfrock, membala wa gulu la eBERlight. �<“我喜欢eBERlight 的多面性，因為它致力于建立一个综合平台，促进跨生物、地球和环境泑结。 �<“我喜欢eBERlight 的多面性，因為它致力于建立一个综合平台，促进跨生物、地球和环境泑结。"Ndimakonda mawonekedwe osiyanasiyana a eBERlight pamene ikuyesetsa kupanga nsanja yophatikizika yomwe imathandizira kafukufuku wasayansi muzinthu zachilengedwe, zapadziko lapansi komanso zachilengedwe.Zikumveka zophweka, koma kukula kwake ndi zotsatira zomwe zingatheke ndi zazikulu.”
Lingaliro la eBERlight lakhala zaka zambiri likupangidwa, malinga ndi Ken Kemner, katswiri wa sayansi ya sayansi komanso mtsogoleri wa gulu ku Argonne National Laboratory.Kemner adagwira ntchito ku APS kwa zaka 27 za labotale, zambiri zomwe adagwiritsa ntchito kulumikiza ofufuza zachilengedwe kuzinthu za bungweli.Tsopano eBERlight ipitiliza ntchitoyi pamlingo waukulu, adatero.Akuyembekezera kuona zinthu zatsopano zomwe zidzachitike kudzera mu kafukufuku wokhudza mpweya wowonjezera kutentha, chilengedwe cha madambo, ndi kugwirizana kwa zomera ndi tizilombo toyambitsa matenda ndi nthaka ndi dothi.
Chinsinsi cha kupambana kwa eBERlight, malinga ndi Kemner, ndi maphunziro a asayansi a synchrotron, komanso asayansi a zamoyo ndi zachilengedwe.
"Muyenera kuphunzitsa akatswiri a radiology kuti amvetse bwino mavuto a sayansi ya chilengedwe ndikusintha teknoloji kuti athetse bwino mavuto ofufuza zachilengedwe," adatero. â�<“您还必须教育环境科学家了解光源设施对于解决這些问题有多么出色. â�<“您还必须教育环境科学家了解光源设施对于解决這些问题有多么出色.“Muyeneranso kuphunzitsa asayansi zachilengedwe za momwe magwero a kuwala alili abwino pothana ndi mavutowa.Izi zimachitidwa pofuna kuchepetsa zopinga zowakopa.”
Laurent Chapon, wachiwiri kwa mkulu wa Photon Science Laboratory ndi mkulu wa APS, adati ndondomeko yatsopanoyi ikutanthauza demokalase kupeza APS ndi mphamvu zake.
"Dongosololi likutumiza uthenga wofunikira kuti APS ndi chida chofunikira kwambiri kwa dzikoli, chomwe chimatha kupanga mapulogalamu omwe amathandiza kuthetsa mavuto ovuta, pankhaniyi mavuto a zachilengedwe ndi zachilengedwe," adatero Chapon. â�<“eBERlight将为寻求解决具有现实世界影响的自然科学的科学家提供端到端解决方案。 â�<“eBERlight将为寻求解决具有现实世界影响的自然科学的科学家提供端到端解决方案。"eBERlight ipereka yankho lathunthu kwa asayansi omwe akufuna kuthana ndi zovuta za sayansi ya moyo zomwe zikufunika."
"Ndikukhulupirira kuti ngakhale asayansi amakumana ndi zovuta zotani, APS ikhoza kuwathandiza," adatero. â�<“這些挑战影响着我們每个人。” â�<“這些挑战影响着我們每个人。”"Nkhani izi zimatikhudza tonsefe."
Argonne Leadership Computing Facility imapatsa gulu lasayansi ndi uinjiniya luso lapamwamba kwambiri kuti lipititse patsogolo kupezedwa kofunikira komanso kumvetsetsa m'machitidwe osiyanasiyana.Mothandizidwa ndi pulogalamu ya US Department of Energy's (DOE) Advanced Scientific Computing Research (ASCR), ALCF ndi amodzi mwa malo awiri otsogola a DOE odzipereka kuti atsegule sayansi.
The US Department of Energy Office of Science's Advanced Photon Source (APS) ku Argonne National Laboratory ndi amodzi mwa magwero opangira ma X-ray padziko lonse lapansi.APS imapereka ma X-ray owala kwambiri ku gulu losiyanasiyana la ofufuza mu sayansi ya zinthu, chemistry, fizikisi ya zinthu zofupikitsidwa, sayansi ya moyo ndi chilengedwe, komanso kafukufuku wogwiritsa ntchito.Ma X-ray awa ndi abwino powerengera zida ndi zinthu zachilengedwe;kugawa zinthu;mankhwala, maginito ndi zamagetsi;komanso makina opangira uinjiniya ofunika kwambiri, kuyambira mabatire kupita ku ma nozzles a jakisoni, omwe ali ofunikira pa chitukuko cha dziko lathu pazachuma, zaukadaulo ndi zachuma.ndi Maziko a chuma chabwino.Chaka chilichonse, ofufuza oposa 5,000 amagwiritsa ntchito APS kupanga zofalitsa zoposa 2,000, kufotokoza zofunikira zomwe zapezedwa ndi kuthetsa mapuloteni ofunika kwambiri achilengedwe kuposa wina aliyense wogwiritsa ntchito malo ofufuzira a X-ray.Ukadaulo waukadaulo wa asayansi ndi mainjiniya a APS amathandizira pakupanga ma accelerator ndi magwero owunikira.Izi zikuphatikizapo zida zolowetsa zomwe zimapanga ma X-ray owala kwambiri omwe akatswiri ofufuza amayamikira, magalasi omwe amayang'ana ma X-ray mpaka ma nanometer ochepa, zida zomwe zimapangitsa kuti ma X-ray azilumikizana kwambiri ndi zitsanzo zomwe zikukambidwa, ndi zida zomwe zimasonkhanitsa ndikusonkhanitsa X. -ray pulogalamu.Sinthani kuchuluka kwa data kuchokera mu maphunziro a APS.
Kafukufukuyu adagwiritsa ntchito zothandizira kuchokera ku Advanced Photon Source, malo ogwiritsira ntchito Ofesi ya DOE ya Sayansi yoyendetsedwa ndi DOE Office of Science's Argonne National Laboratory pansi pa Contract No. DE-AC02-06CH11357.
Argonne National Laboratory yadzipereka kuthana ndi zovuta zasayansi ndi ukadaulo wadziko lonse.Argonne National Laboratory, labotale yoyamba ku United States, imachita kafukufuku wasayansi wotsogola komanso wogwiritsa ntchito pafupifupi gawo lililonse la sayansi.Ofufuza a Argonne National Laboratory amagwira ntchito limodzi ndi ofufuza ochokera kumakampani mazanamazana, mayunivesite, ndi mabungwe aboma, maboma ndi ma municipalities kuti awathandize kuthetsa mavuto enaake, kupititsa patsogolo utsogoleri wa sayansi ku US, ndikupanga tsogolo labwino la dziko.Argonne ali ndi antchito amitundu yopitilira 60 ndipo amayang'aniridwa ndi Argonne LLC ku Chicago, gawo la US Department of Energy's Office of Science.
Ofesi ya Sayansi ya Dipatimenti ya Zamagetsi ku United States ndi amene amapereka ndalama zambiri pa kafukufuku wa sayansi ya zinthu zakuthupi ku United States ndipo akuyesetsa kuthana ndi mavuto amene akukumana nawo masiku ano.Kuti mudziwe zambiri, pitani ku https://energygy.gov/science.
Nthawi yotumiza: Nov-06-2023